This time around, we'll be accompanied by Dogmeat, our loyal and indestructible canine friend. Get ready for a new installment of one of the most successful action games, that takes us back to a post-apocalyptic world full of enemies that we'll have to fight against. New challenges and new missions to be completed. Fallout 4 is set in New England and, despite the action taking place in the 25th century, the storyline starts on October 23rd, 2077, the date of the nuclear catastrophe, when we took shelter in Vault 111, which we didn't leave until two centuries later. The fourth installment of the Fallout saga takes place 200 years after the nuclear holocaust of 2077.